BDBM50055876 4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-piperidine::CHEMBL20648

SMILES Fc1ccc(CN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)cc1

InChI Key InChIKey=XNPXCWOQSAQIEL-UHFFFAOYSA-N

Data  2 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50055876   

LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 1.92E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 17.2nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 37.6nMAssay Description:Affinity was evaluated using [3H]WIN-35428 (radioligand) on Cloned human Dopamine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 1.92E+3nMAssay Description:IC50 value was evaluated using [3H]citalopram (radioligand) on serotonin transporter in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 17.2nMAssay Description:IC50 value was evaluated using [3H]WIN-35428 (radioligand) on Dopamine transporter in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 17.2nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 1.92E+3nMAssay Description:In vitro binding affinity at serotonin transporter in rat striatum by [3H]- citalopram displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 2.48nMAssay Description:Inhibition of uptake from dopamine transporter in rat striatum using [3H]DA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 17.2nMAssay Description:Binding affinity towards dopamine transporter in rat striatum using [3H]WIN-35 428 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 1.92E+3nMAssay Description:Binding affinity towards serotonin transporter in rat striatum using [3H]citalopram as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataKi:  5.10nMAssay Description:Affinity at rat dopamine transporter using [125I]RTI-55 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataKi:  902nMAssay Description:Affinity at rat serotonin transporter using [125I]RTI-55 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed