BDBM50055648 10-[2-[1-(Methoxymethyl)-4-[1-(methoxymethyl)-4-butyramidopyrrole-2-carboxamido]pyrrole-2-carboxamido]ethoxy]-20(R,S)-camptothecin::CHEMBL74406

SMILES CCCC(=O)Nc1cc(C(=O)Nc2cc(C(=O)NCCOc3ccc4nc-5c(Cn6c-5cc5c(COC(=O)C5(O)CC)c6=O)cc4c3)n(COC)c2)n(COC)c1

InChI Key InChIKey=QVSHBSMUJLKADQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055648   

TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055648(10-[2-[1-(Methoxymethyl)-4-[1-(methoxymethyl)-4-bu...)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed