BDBM50055383 (3-Aminooxalyl-1-benzyl-2-methyl-1H-indol-4-yloxy)-acetic acid::2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hindol-4-yloxy)acetic acid::CHEMBL346196

SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1

InChI Key InChIKey=FBGWHCFPQBQYNU-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50055383   

TargetGroup 10 secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant sPLA2 G10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 15nMAssay Description:Inhibition of pig group IB phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhospholipase A2(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 761nMAssay Description:Inhibition of human group IB phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human group IIA phospholipase A2 incubated for 1 hrs by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGroup 10 secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of mouse recombinant sPLA2 G10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 275nMAssay Description:Inhibition of human recombinant sPLA2 G2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant sPLA2 G1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGroup IIE secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 400nMAssay Description:Inhibition of mouse recombinant sPLA2 G2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2 group V(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse recombinant sPLA2 G5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGroup IIE secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant sPLA2 G2EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2 group V(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant sPLA2 G5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of mouse recombinant sPLA2 G1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 761nMAssay Description:Compound was tested for inhibition of human secretory pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Niddk

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 15nMAssay Description:Compound was tested for inhibition of porcine secretory pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50055383(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-methyl-1Hind...)
Affinity DataIC50: 125nMAssay Description:Inhibition of mouse recombinant sPLA2 G2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed