BDBM50055305 CHEMBL423762::Sodium; (1-biphenyl-2-ylmethyl-3-carbamoylmethyl-2-methyl-1H-indol-4-yloxy)-acetate

SMILES Cc1c(CC(N)=O)c2c(OCC([O-])=O)cccc2n1Cc1ccccc1-c1ccccc1

InChI Key InChIKey=JWYKXMWKTRAUDI-UHFFFAOYSA-M

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50055305   

TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055305(Sodium; (1-biphenyl-2-ylmethyl-3-carbamoylmethyl-2...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against porcine pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055305(Sodium; (1-biphenyl-2-ylmethyl-3-carbamoylmethyl-2...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50055305(Sodium; (1-biphenyl-2-ylmethyl-3-carbamoylmethyl-2...)
Affinity DataIC50: 4.09E+3nMAssay Description:Inhibitory activity against human pancreatic Phospholipase A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed