BDBM50055002 5-(4-Chloro-phenyl)-2,2-dimethyl-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol::CHEMBL337299

SMILES CC1(C)CN2C(=N1)c1ccccc1C2(O)c1ccc(Cl)cc1

InChI Key InChIKey=XEUNLTQABDZKBW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50055002   

TargetSodium-dependent dopamine transporter(Rat)
Drew University

Curated by ChEMBL
LigandPNGBDBM50055002(5-(4-Chloro-phenyl)-2,2-dimethyl-2,5-dihydro-3H-im...)
Affinity DataIC50: 106nMAssay Description:Compound was tested for inhibition of [3H]dopamine uptake at the dopamine transporter in rat strial tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Drew University

Curated by ChEMBL
LigandPNGBDBM50055002(5-(4-Chloro-phenyl)-2,2-dimethyl-2,5-dihydro-3H-im...)
Affinity DataIC50: 50.4nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporter in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Drew University

Curated by ChEMBL
LigandPNGBDBM50055002(5-(4-Chloro-phenyl)-2,2-dimethyl-2,5-dihydro-3H-im...)
Affinity DataIC50: 50nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed