BDBM50054747 ((S)-1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-pyrrolidin-2-ylmethyl)-(3-phenyl-propyl)-amine::CHEMBL141251

SMILES Fc1ccc(cc1)C(OCCN1CCC[C@H]1CNCCCc1ccccc1)c1ccc(F)cc1

InChI Key InChIKey=RNMMMKSJGRTVQB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054747   

TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054747(((S)-1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-p...)
Affinity DataIC50: 29nMAssay Description:Inhibition of dopamine DA reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054747(((S)-1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-p...)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of [3H]5-HT reuptake at rat serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054747(((S)-1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-p...)
Affinity DataIC50: 104nMAssay Description:Binding against Dopamine transporter using radioligand as [3H]GBR 12935More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed