BDBM50054736 CHEMBL140104::N-(2-Benzhydryloxy-ethyl)-N'-(3-phenyl-propyl)-butane-1,4-diamine

SMILES C(CCNCCOC(c1ccccc1)c1ccccc1)CNCCCc1ccccc1

InChI Key InChIKey=DKFCKRNSTGLFQA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054736   

TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054736(N-(2-Benzhydryloxy-ethyl)-N'-(3-phenyl-propyl)-but...)
Affinity DataIC50: 80nMAssay Description:Binding against Dopamine transporter using radioligand as [3H]GBR 12935More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054736(N-(2-Benzhydryloxy-ethyl)-N'-(3-phenyl-propyl)-but...)
Affinity DataIC50: 376nMAssay Description:Inhibition of [3H]5-HT reuptake at rat serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054736(N-(2-Benzhydryloxy-ethyl)-N'-(3-phenyl-propyl)-but...)
Affinity DataIC50: 35nMAssay Description:Inhibition of dopamine DA reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054736(N-(2-Benzhydryloxy-ethyl)-N'-(3-phenyl-propyl)-but...)
Affinity DataIC50: 1.05E+3nMAssay Description:Binding affinity against sigma receptor using radioligand ([3H](+)-pentazocine) binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed