BDBM50054735 CHEMBL142041::N-(2-Benzhydryloxy-ethyl)-N,N'-dimethyl-N'-(3-phenyl-propyl)-ethane-1,2-diamine

SMILES CN(CCCc1ccccc1)CCN(C)CCOC(c1ccccc1)c1ccccc1

InChI Key InChIKey=RLHULZKZUDFBGK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054735   

TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054735(N-(2-Benzhydryloxy-ethyl)-N,N'-dimethyl-N'-(3-phen...)
Affinity DataIC50: 27nMAssay Description:Binding affinity against dopamine transporter using radioligand as [3H]GBR 12935More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054735(N-(2-Benzhydryloxy-ethyl)-N,N'-dimethyl-N'-(3-phen...)
Affinity DataIC50: 34nMAssay Description:Binding affinity against sigma receptor using radioligand ([3H](+)-pentazocine) binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054735(N-(2-Benzhydryloxy-ethyl)-N,N'-dimethyl-N'-(3-phen...)
Affinity DataIC50: 18nMAssay Description:Inhibition of dopamine DA reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054735(N-(2-Benzhydryloxy-ethyl)-N,N'-dimethyl-N'-(3-phen...)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of [3H]5-HT reuptake at rat serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed