BDBM50054729 (2S,5R)-2,5-Dimethyl-1,4-bis-(3-phenyl-propyl)-piperazine::CHEMBL348432

SMILES C[C@H]1CN(CCCc2ccccc2)[C@H](C)CN1CCCc1ccccc1

InChI Key InChIKey=LKOCZDGKQPKBPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054729   

TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054729((2S,5R)-2,5-Dimethyl-1,4-bis-(3-phenyl-propyl)-pip...)
Affinity DataIC50: 9.94E+3nMAssay Description:Binding affinity against dopamine transporter using radioligand as [3H]GBR 12935More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054729((2S,5R)-2,5-Dimethyl-1,4-bis-(3-phenyl-propyl)-pip...)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of dopamine DA reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054729((2S,5R)-2,5-Dimethyl-1,4-bis-(3-phenyl-propyl)-pip...)
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of [3H]5-HT reuptake at rat serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054729((2S,5R)-2,5-Dimethyl-1,4-bis-(3-phenyl-propyl)-pip...)
Affinity DataIC50: 8.5nMAssay Description:Binding affinity against sigma receptor using radioligand ([3H](+)-pentazocine) binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed