BDBM50054723 1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-((E)-3-phenyl-allyl)-[1,4]diazepane::CHEMBL143823

SMILES Fc1ccc(cc1)C(OCCN1CCCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=XXURTKGAFDGDML-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054723   

TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054723(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-((E)...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of dopamine DA reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054723(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-((E)...)
Affinity DataIC50: 2.60nMAssay Description:Binding against Dopamine transporter using radioligand as [3H]GBR 12935More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50054723(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-((E)...)
Affinity DataIC50: 234nMAssay Description:Inhibition of [3H]5-HT reuptake at rat serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed