BDBM50054517 (S)-2-{[5-(5-Fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy]-hydroxy-phosphorylamino}-3-phenyl-propionic acid methyl ester::CHEMBL96148

SMILES COC(=O)[C@H](Cc1ccccc1)NP(O)(=O)OCC1OC(CC1O)n1cc(F)c(=O)[nH]c1=O

InChI Key InChIKey=HFEXLDAKJKRVGR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50054517   

TargetThymidylate synthase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50054517((S)-2-{[5-(5-Fluoro-2,4-dioxo-3,4-dihydro-2H-pyrim...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of cellular thymidylate synthase activity of mouse fibroblast (L929 TK-) in intact cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50054517((S)-2-{[5-(5-Fluoro-2,4-dioxo-3,4-dihydro-2H-pyrim...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of cellular thymidylate synthase activity of mouse fibroblast (L929 TK-) in permeabilised cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50054517((S)-2-{[5-(5-Fluoro-2,4-dioxo-3,4-dihydro-2H-pyrim...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of cellular thymidylate synthase activity of murine leukemia cell line (L1210) in intact cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50054517((S)-2-{[5-(5-Fluoro-2,4-dioxo-3,4-dihydro-2H-pyrim...)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of cellular thymidylate synthase activity of human leukemia cell line(CCRF-CEM). More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50054517((S)-2-{[5-(5-Fluoro-2,4-dioxo-3,4-dihydro-2H-pyrim...)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of cellular thymidylate synthase activity of human leukemia cell line(CCRF-CEM). More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50054517((S)-2-{[5-(5-Fluoro-2,4-dioxo-3,4-dihydro-2H-pyrim...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of cellular thymidylate synthase activity of murine leukemia cell line (L1210) in permeabilised cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed