BDBM50054514 2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL57310

SMILES Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccncc1

InChI Key InChIKey=UDVUNRHQICGCBT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50054514   

TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50: 340nMAssay Description:Compound was evaluated for the inhibition at a given concentration against recombinant human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for the inhibition at a given concentration against Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50: 340nMAssay Description:The inhibitory concentration of compound was evaluated on Human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50: 2.90E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Escherichia coli Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50: 2.90E+4nMAssay Description:The inhibitory concentration of compound was evaluated on Streptococcus faecium Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibitory concentration of compound was evaluated on Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50054514(2-Amino-6-methyl-5-(pyridin-4-ylsulfanyl)-3,7-dihy...)
Affinity DataIC50: 340nMAssay Description:Inhibitory concentration against human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed