BDBM50054214 2-{4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-amino]-benzoylamino}-3-(1H-imidazol-4-yl)-propionic acid::CHEMBL137370

SMILES Nc1nc2ncc(CNc3ccc(cc3)C(=O)NC(Cc3cnc[nH]3)C(O)=O)nc2c(=O)[nH]1

InChI Key InChIKey=FKVRTWTUJJKJFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054214   

TargetDihydrofolate reductase(Mouse)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50054214(2-{4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-amin...)
Affinity DataIC50: 1.00E+5nMAssay Description:compound was evaluated for the inhibitory activity against Dihydrofolate reductase in permeabilised L1210 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFolylpolyglutamate synthase, mitochondrial(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50054214(2-{4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-amin...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibitory activity against Folyl-polyglutamate synthase from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed