BDBM50054213 3-(1-Carboxymethyl-1H-imidazol-4-yl)-2-{4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-propionic acid::CHEMBL136133

SMILES CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)NC(Cc1cn(CC(O)=O)cn1)C(O)=O

InChI Key InChIKey=WIYBYBVRQRKSMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054213   

TargetFolylpolyglutamate synthase, mitochondrial(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50054213(3-(1-Carboxymethyl-1H-imidazol-4-yl)-2-{4-[(2,4-di...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibitory activity against Folyl-polyglutamate synthase from CCRF-CEM human leukemia cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Mouse)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50054213(3-(1-Carboxymethyl-1H-imidazol-4-yl)-2-{4-[(2,4-di...)
Affinity DataIC50: 370nMAssay Description:compound was evaluated for the inhibitory activity against Dihydrofolate reductase in permeabilised L1210 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed