BDBM50053829 CHEMBL134179::{1-[1-Benzyl-2-(2-hydroxy-2-phenyl-ethylcarbamoyl)-2-oxo-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester

SMILES CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NCC(O)c1ccccc1

InChI Key InChIKey=ZTHSETGUYKRPPC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50053829   

TargetCalpain-2 catalytic subunit(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50053829({1-[1-Benzyl-2-(2-hydroxy-2-phenyl-ethylcarbamoyl)...)
Affinity DataKi:  50nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50053829({1-[1-Benzyl-2-(2-hydroxy-2-phenyl-ethylcarbamoyl)...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50053829({1-[1-Benzyl-2-(2-hydroxy-2-phenyl-ethylcarbamoyl)...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed