BDBM50053596 1-phenylbiguanide::CHEMBL13791::N-phenylimidodicarbonimidic diamide::Phenyl biguanide

SMILES NC(=N)NC(N)=Nc1ccccc1

InChI Key InChIKey=CUQCMXFWIMOWRP-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50053596   

TargetIntegrin alpha-V/beta-3(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50053596(1-phenylbiguanide | Phenyl biguanide | N-phenylimi...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of integrin alphavbeta3 mediated cell adhesion of human M21 cells to vitronectinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTrace amine-associated receptor 5(Mouse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50053596(1-phenylbiguanide | Phenyl biguanide | N-phenylimi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053596(1-phenylbiguanide | Phenyl biguanide | N-phenylimi...)
Affinity DataKi:  1.20E+3nMAssay Description:Compound was tested for the inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed