BDBM50053435 CHEMBL3323035

SMILES C(COc1ccc2N=C3CCCN3Cc2c1)CN1CCCCC1

InChI Key InChIKey=UVYNECUSQBZMSD-UHFFFAOYSA-N

Data  5 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50053435   

TargetAcetylcholinesterase(Human)
Universit£T Regensburg

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 34nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 122nMAssay Description:Inhibition of equine serum BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 69nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Universit£T Regensburg

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of equine serum BChE using BTC iodide as substrate preincubated with enzyme for 4.5 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 67nMAssay Description:Inhibition of Electric eel AChE using ATC iodide as substrate preincubated with enzyme for 4.5 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universit£T Regensburg

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 34nMAssay Description:Inhibition of human erythrocyte AChE using ATC iodide as substrate preincubated with enzyme for 4.5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate preincubated for 4.5 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 67nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine chloride as substrate preincubated for 4.5 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 67nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universit£T Regensburg

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 34nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of equine BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataIC50: 67nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]histamine from human histamine H3 receptor expressed in Sf9 insect cell membranes after 60 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]-Histamine from human histamine H3 receptor expressed in Sf9 cells incubated for 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataKi:  76nMAssay Description:Displacement of [3H]histamine from human histamine H3 receptor expressed in Sf9 insect cell membranes after 60 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataKi:  76nMAssay Description:Inhibition of human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50053435(CHEMBL3323035)
Affinity DataKi:  76nMAssay Description:Inhibition of human H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed