BDBM50051837 CHEMBL3318359

SMILES Clc1ccc(C(Cn2ccnc2)OCc2cccnc2)c(Cl)c1

InChI Key InChIKey=LZLUUFLNJANHEW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051837   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50051837(CHEMBL3318359)
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins in presence of 0.01% Triton-X by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2016
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Southwest University

Curated by ChEMBL
LigandPNGBDBM50051837(CHEMBL3318359)
Affinity DataIC50: 4.17E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Southwest University

Curated by ChEMBL
LigandPNGBDBM50051837(CHEMBL3318359)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of electric eel AChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Swiss Institute of Bioinformatics

Curated by ChEMBL
LigandPNGBDBM50051837(CHEMBL3318359)
Affinity DataIC50: 9.45E+4nMAssay Description:Inhibition of human N-terminal IDO1 expressed in Escherichia coli BL21 A1 cells using L-tryptophan as substrate measured after 30 mins by HPLC analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed