BDBM50051562 1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-piperazine::CHEMBL71724

SMILES COc1ccc(cc1)N1CCN(CCC2OCCc3ccccc23)CC1

InChI Key InChIKey=IAUNACXRZSWWJT-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50051562   

TargetD(4) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity of [3H]spiperone towards Dopamine receptor D4 expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi:  2.40nMAssay Description:The compound was tested for CNS binding affinity towards Dopamine receptor D4 from cloned Human membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi:  6.70nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1D receptor from cloned gorilla membranes expressed in cultured HEK 293 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi:  76nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 2A receptor from cloned Human membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi:  899nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1A receptor from cloned Human membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity of [3H]U-86170 towards Dopamine receptor D2 in cloned mammalian receptor expressed in cultured cells or from rat whole brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity of [3H]-8-OH-DPAT towards 5-hydroxytryptamine 1A receptor in cloned mammalian receptor expressed in cultured cells or from rat whole...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity of [3H]spiperone towards Dopamine receptor D3 in cloned mammalian receptor expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi:  1.43E+3nMAssay Description:The compound was tested for CNS binding affinity towards Dopamine receptor D2 from cloned Human membranes.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi: >2.40E+3nMAssay Description:Binding affinity of [3H]SCH-23,390 towards Dopamine receptor D1 in cloned mammalian receptor expressed in cultured cells or from rat whole brain.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Western lowland gorilla)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50051562(1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-p...)
Affinity DataKi:  7.24E+3nMAssay Description:The compound was tested for CNS binding affinity towards 5-hydroxytryptamine 1B receptor from cloned gorilla membranes expressed in cultured HEK 293 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed