BDBM50051496 CHEMBL310228::[(S)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-[(1R,2S)-2-(3-trifluoromethyl-phenyl)-cyclopropyl]-methanone

SMILES FC(F)(F)c1cccc(c1)[C@H]1C[C@H]1C(=O)N1C2CCC(CC2)[C@H]1C(=O)N1CCCC1

InChI Key InChIKey=NYESJNSEALKTLB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051496   

TargetProlyl endopeptidase(Rat)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50051496([(S)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2....)
Affinity DataIC50: 3.20nMAssay Description:Inhibitory activity was evaluated against Post-proline cleaving enzyme from rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed