BDBM50051484 CHEMBL307938::[(S)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-((1R,2S)-2-thiophen-2-yl-cyclopropyl)-methanone

SMILES O=C([C@@H]1C2CCC(CC2)N1C(=O)[C@@H]1C[C@@H]1c1cccs1)N1CCCC1

InChI Key InChIKey=BWQBQKNYEMXWRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051484   

TargetProlyl endopeptidase(Rat)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50051484([(S)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2....)
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity was evaluated against Post-proline cleaving enzyme from rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Institut De Recherche Servier

Curated by ChEMBL
LigandPNGBDBM50051484([(S)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2....)
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity was evaluated against Post-proline cleaving enzyme from Flavobacterium meningosepticumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed