BDBM50051389 CHEMBL74277::[8-(2-Bromo-1H-indol-3-ylmethyl)-14-cyclopentyl-11-cyclopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid

SMILES OC(=O)C[C@H]1NC(=O)[C@H](Cc2c(Br)[nH]c3ccccc23)NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C1=O)C1CCCC1)C1CC1

InChI Key InChIKey=OBNJEEOFTPJHQY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051389   

TargetEndothelin receptor type B(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051389([8-(2-Bromo-1H-indol-3-ylmethyl)-14-cyclopentyl-11...)
Affinity DataIC50: 29nMAssay Description:Binding affinity towards Endothelin B receptor in human girardi heart cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051389([8-(2-Bromo-1H-indol-3-ylmethyl)-14-cyclopentyl-11...)
Affinity DataIC50: 8.60nMAssay Description:Binding affinity towards Endothelin A receptor in human neuroblastoma-derived cell line SK-N-MC membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051389([8-(2-Bromo-1H-indol-3-ylmethyl)-14-cyclopentyl-11...)
Affinity DataIC50: 15nMAssay Description:Binding affinity towards endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50051389([8-(2-Bromo-1H-indol-3-ylmethyl)-14-cyclopentyl-11...)
Affinity DataIC50: 4.90nMAssay Description:Binding affinity towards endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2012
Entry Details Article
PubMed