BDBM50051143 2-[(R)-3-(2-Morpholin-4-yl-ethyl)-2,4,8-trioxo-6-phenyl-2,3,4,8-tetrahydro-1H-pyrido[3,4-d]pyrimidin-7-yl]-N-(3,3,3-trifluoro-1-isopropyl-2-oxo-propyl)-acetamide::CHEMBL14293

SMILES CC(C)C(NC(=O)Cn1c(cc2c([nH]c(=O)n(CCN3CCOCC3)c2=O)c1=O)-c1ccccc1)C(=O)C(F)(F)F

InChI Key InChIKey=UBYXQHGKGLHIOW-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051143   

TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051143(2-[(R)-3-(2-Morpholin-4-yl-ethyl)-2,4,8-trioxo-6-p...)
Affinity DataKi:  8.40nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed