BDBM50050624 6-(5-Dimethylamino-2-propoxy-phenyl)-1-ethyl-3-methyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one::CHEMBL42776

SMILES CCCOc1ccc(cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1)N(C)C

InChI Key InChIKey=ALYKWZQKEAKZMJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050624   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050624(CHEMBL42776 | 6-(5-Dimethylamino-2-propoxy-phenyl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Phosphodiesterase 5 from humanMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Laboratories Glaxo Wellcome Centre De Recherches

Curated by ChEMBL
LigandPNGBDBM50050624(CHEMBL42776 | 6-(5-Dimethylamino-2-propoxy-phenyl)...)
Affinity DataEC50:  1.50E+3nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed