BDBM50050472 4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethyl-piperidine::4-[5-(4-Chloro-phenyl)-2H-pyrazol-3-yl]-1-phenethyl-piperidine::CHEMBL6416

SMILES Clc1ccc(cc1)-c1cc([nH]n1)C1CCN(CCc2ccccc2)CC1

InChI Key InChIKey=YCDXELFFFUYKMO-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50050472   

TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050472(4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethy...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050472(4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethy...)
Affinity DataKi:  5.5nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D4 (hD4) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050472(4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethy...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity towards human dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050472(4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethy...)
Affinity DataKi:  520nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050472(4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethy...)
Affinity DataKi:  520nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D2 stably expressed in CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050472(4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethy...)
Affinity DataKi: >4.00E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50050472(4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethy...)
Affinity DataKi: >4.00E+3nMAssay Description:Ability to displace [3H]spiperone from human dopamine receptor D3 (hD3) receptor stably expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed