BDBM50050080 CHEMBL3317830::US9216988, 24

SMILES CC(C)CN(Cc1ccc(cc1)N1CCC(CC1)C#N)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=KMYLNORLILVEAB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050080   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM50050080(US9216988, 24 | CHEMBL3317830)
Affinity DataIC50: 96nMpH: 7.4Assay Description:On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash buff...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM50050080(US9216988, 24 | CHEMBL3317830)
Affinity DataEC50:  74nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed