BDBM50050072 CHEMBL3317733::US9216988, 100

SMILES CC(C)CN(Cc1ccc(cc1)N1CCN(CC1)S(C)(=O)=O)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=KOOGMTWQJLVJND-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050072   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM50050072(US9216988, 100 | CHEMBL3317733)
Affinity DataIC50: 118nMpH: 7.4Assay Description:On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM50050072(US9216988, 100 | CHEMBL3317733)
Affinity DataEC50:  210nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2016
Entry Details Article
PubMed