BDBM50050048 5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-4-methyl-2-[3-(4-methyl-cyclohexyl)-ureido]-pentanoylamino}-ethyl)-oxazole-4-carboxylic acid::CHEMBL177195

SMILES CC(C)C[C@H](NC(=O)NC1CCC(C)CC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1

InChI Key InChIKey=CUXQJQJNEAEYGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050048   

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050048(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050048(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity was evaluated against ET- B Binding to Endothelin B receptor from porcine cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed