BDBM50050040 Azepane-1-carboxylic acid {(S)-1-[(R)-2-(1H-indol-3-yl)-1-(5-methyl-4-methylcarbamoyl-oxazol-2-yl)-ethylcarbamoyl]-3-methyl-butyl}-amide::CHEMBL176565

SMILES CNC(=O)c1nc(oc1C)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)N1CCCCCC1

InChI Key InChIKey=GJMWRNQOTARVKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050040   

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050040(Azepane-1-carboxylic acid {(S)-1-[(R)-2-(1H-indol-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050040(Azepane-1-carboxylic acid {(S)-1-[(R)-2-(1H-indol-...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibitory activity was evaluated against ET- B Binding to Endothelin B receptor from porcine cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed