BDBM50050029 2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pentanoylamino]-2-(1-ethyl-1H-indol-3-yl)-ethyl]-5-methyl-1H-imidazole-4-carboxylic acid::CHEMBL174686

SMILES CCn1cc(C[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)NC2CCCCC2)c2nc(C(O)=O)c(C)[nH]2)c2ccccc12

InChI Key InChIKey=QBIDYURNSVUVBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050029   

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050029(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)
Affinity DataIC50: 730nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050029(2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibitory activity was evaluated against ET- B Binding to Endothelin B receptor from porcine cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed