BDBM50050002 5-Methyl-2-{(R)-2-(1-methyl-1H-indol-3-yl)-1-[(S)-4-methyl-2-(3-pyridin-2-yl-ureido)-pentanoylamino]-ethyl}-oxazole-4-carboxylic acid::CHEMBL369386

SMILES CC(C)C[C@H](NC(=O)Nc1ccccn1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1

InChI Key InChIKey=RHFGRSNVCQCNLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050002   

TargetEndothelin-1 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050002(5-Methyl-2-{(R)-2-(1-methyl-1H-indol-3-yl)-1-[(S)-...)
Affinity DataIC50: 74nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050002(5-Methyl-2-{(R)-2-(1-methyl-1H-indol-3-yl)-1-[(S)-...)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibitory activity was evaluated against ET- B Binding to Endothelin B receptor from porcine cerebellar membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed