BDBM50049624 6-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-2,3-dihydro-benzo[1,4]dioxine::CHEMBL54746

SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(F)c(F)cc1-c1ccc2OCCOc2c1

InChI Key InChIKey=DLEXWYPUXDTMQV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049624   

TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049624(6-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049624(6-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-...)
Affinity DataIC50: 340nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50049624(6-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-...)
Affinity DataIC50: 339nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed