BDBM50049313 2-Dimethylamino-N-{3-(1H-indol-3-yl)-2-[2-(4-phenyl-piperazin-1-yl)-acetylamino]-propyl}-N-(2-methoxy-benzyl)-acetamide::CHEMBL350151

SMILES COc1ccccc1CN(CC(Cc1c[nH]c2ccccc12)NC(=O)CN1CCN(CC1)c1ccccc1)C(=O)CN(C)C

InChI Key InChIKey=BPOJDIXXCVFYFB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049313   

TargetSubstance-P receptor(Mouse)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049313(2-Dimethylamino-N-{3-(1H-indol-3-yl)-2-[2-(4-pheny...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against Tachykinin receptor 1 in mouse brain using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049313(2-Dimethylamino-N-{3-(1H-indol-3-yl)-2-[2-(4-pheny...)
Affinity DataIC50: 480nMAssay Description:Inhibitory activity against Tachykinin receptor 1 in rat brain using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049313(2-Dimethylamino-N-{3-(1H-indol-3-yl)-2-[2-(4-pheny...)
Affinity DataIC50: 1.54nMAssay Description:Inhibitory activity against Tachykinin receptor 1 in human IM-9 cells using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed