BDBM50049206 5-Ethyl-3-(3-fluoro-2'-isopentyloxycarbaronylsulfamoyl-biphenyl-4-ylmethyl)-2-propyl3H-imidazole-4-carboxylicacid2-benzoyl-benzyl ester(EXP597)::Biphenylsulfonylcarbamate compound::CHEMBL74573

SMILES CCCc1nc(CC)c(C(=O)OCc2ccccc2C(=O)c2ccccc2)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C

InChI Key InChIKey=RHPYOBNZBPQRBD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50049206   

TargetType-1 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50049206(Biphenylsulfonylcarbamate compound | 5-Ethyl-3-(3-...)
Affinity DataIC50: 0.5nMAssay Description:Binding affinity for Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50049206(Biphenylsulfonylcarbamate compound | 5-Ethyl-3-(3-...)
Affinity DataIC50: 0.700nMAssay Description:Binding affinity for angiotensin II AT-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50049206(Biphenylsulfonylcarbamate compound | 5-Ethyl-3-(3-...)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of Angiotensin II receptor, type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50049206(Biphenylsulfonylcarbamate compound | 5-Ethyl-3-(3-...)
Affinity DataIC50: 570nMAssay Description:Inhibition of Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed