BDBM50049171 2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-butyrylamino)-pentanedioic acidTFA. 0.7 Et2O::CHEMBL352357

SMILES Cc1nc2ccc(CN(CC#C)c3ccc(cc3)C(=O)N[C@@H](CCC(=O)NC(Cc3ccccc3)C(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=FKYIVZFRSYLENF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049171   

TargetThymidylate synthase(Mouse)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049171(2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dihydro-qui...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Thymidylate synthase activity in L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed