BDBM50048009 5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-3H-[1,3,4]thiadiazole-2-thione::5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[1,3,4]thiadiazole-2-thiol::CHEMBL417022

SMILES Cc1ccc(Cl)c(Nc2ccccc2-c2nnc(S)s2)c1Cl

InChI Key InChIKey=GSDDMNUUKSXZMH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50048009   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048009(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048009(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50: 1.39E+3nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50048009(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50: 1.75E+3nMAssay Description:In vitro inhibitory activity against Cyclooxygenase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50048009(5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-[...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase mediated PGF2-alpha formation in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed