BDBM50047595 1-Butyl-3-{2-[3-(5-isopropyl-4-phenyl-imidazol-1-yl)-propoxy]-6-methyl-phenyl}-urea::CHEMBL46450

SMILES CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1C(C)C)-c1ccccc1

InChI Key InChIKey=WUUHIJKNNRVBCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50047595   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047595(1-Butyl-3-{2-[3-(5-isopropyl-4-phenyl-imidazol-1-y...)
Affinity DataIC50: 12nMAssay Description:Tested for inhibition against Acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate (>, denotes no effect at the concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Eisai

Curated by ChEMBL
LigandPNGBDBM50047595(1-Butyl-3-{2-[3-(5-isopropyl-4-phenyl-imidazol-1-y...)
Affinity DataIC50: 130nMAssay Description:Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed