BDBM50047184 1,3-Diethyl-7-methyl-8-[(E)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-3,7-dihydro-purine-2,6-dione::1,3-Diethyl-7-methyl-8-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-3,7-dihydro-purine-2,6-dione::CHEMBL422399

SMILES CCn1c2nc(\C=C\c3cc(OC)c(OC)c(OC)c3)n(C)c2c(=O)n(CC)c1=O

InChI Key InChIKey=ZUVCBMUGYDVTKR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50047184   

TargetAdenosine receptor A2a(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50047184(1,3-Diethyl-7-methyl-8-[2-(3,4,5-trimethoxy-phenyl...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]-CGS- 21680 from Adenosine A2a receptor of rat forebrain membranes (shielded from light)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetAdenosine receptor A2a(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50047184(1,3-Diethyl-7-methyl-8-[2-(3,4,5-trimethoxy-phenyl...)
Affinity DataKi:  6.20nMAssay Description:In vitro binding affinity against Adenosine A2a receptor in rat forebrain membranes by [3H]NECA (+CPA) displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetAdenosine receptor A2a/A2b(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50047184(1,3-Diethyl-7-methyl-8-[2-(3,4,5-trimethoxy-phenyl...)
Affinity DataKi:  81nMAssay Description:Binding affinity against adenosine A2 receptor in rat brain using [3H]- CGS 21680 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50047184(1,3-Diethyl-7-methyl-8-[2-(3,4,5-trimethoxy-phenyl...)
Affinity DataKi:  2.79E+3nMAssay Description:Binding affinity at Adenosine A1 receptor in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed