BDBM50047005 1-Aza-bicyclo[2.2.2]octan-3-ol::1-Aza-bicyclo[2.2.2]octan-3-ol (3-quinuclidinol)::3-hydroxy-1-azoniabicyclo[2.2.2]octane::CHEMBL276310

SMILES OC1CN2CCC1CC2

InChI Key InChIKey=IVLICPVPXWEGCA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50047005   

TargetCytochrome P450 2D6(Human)
Institut F£R Toxikologie

Curated by ChEMBL
LigandPNGBDBM50047005(1-Aza-bicyclo[2.2.2]octan-3-ol (3-quinuclidinol) |...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory effect on Bufuralol 1'-hydroxylation by human liver microsomes (Ki = apparent inhibition constant)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rat)
Texas Tech University Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50047005(1-Aza-bicyclo[2.2.2]octan-3-ol (3-quinuclidinol) |...)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of [3H]choline brain uptake through choline transporter was determined in situ brain perfusion studies in Male Fischer-344 ratsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHigh affinity choline transporter 1(Mouse)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50047005(1-Aza-bicyclo[2.2.2]octan-3-ol (3-quinuclidinol) |...)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of [3H]choline uptake at choline transporter 1 in mouse brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed