BDBM50046918 2,6-Di-tert-butyl-4-[(E)-2-(5-mercapto-[1,3,4]thiadiazol-2-yl)-vinyl]-phenol::5-[2-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-vinyl]-3H-[1,3,4]thiadiazole-2-thione::CHEMBL94851

SMILES CC(C)(C)c1cc(C=Cc2nnc(S)s2)cc(c1O)C(C)(C)C

InChI Key InChIKey=ZWGTUOQMKRRRNZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50046918   

LigandPNGBDBM50046918(2,6-Di-tert-butyl-4-[(E)-2-(5-mercapto-[1,3,4]thia...)
Affinity DataIC50: 1.80E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50046918(2,6-Di-tert-butyl-4-[(E)-2-(5-mercapto-[1,3,4]thia...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 5-lipoxygenase measured by the reduction of leukotriene B4 (LTB4) in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50046918(2,6-Di-tert-butyl-4-[(E)-2-(5-mercapto-[1,3,4]thia...)
Affinity DataIC50: 5.20E+3nMAssay Description:The compound was tested for the inhibition of Prostaglandin G/H synthase in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article