BDBM50046187 CHEMBL3311228

SMILES O[C@@](Cn1cnnn1)(c1ccc(F)cc1F)C(F)(F)c1ccc(cn1)-c1ccc(OCC(F)(F)F)cc1

InChI Key InChIKey=IDUYJRXRDSPPRC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50046187   

TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046187(CHEMBL3311228)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of CYP3A4 in human hepatocytes using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046187(CHEMBL3311228)
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046187(CHEMBL3311228)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046187(CHEMBL3311228)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of CYP3A4 in human hepatocyte microsomes using testosterone substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2020
Entry Details Article
PubMed