BDBM50045831 CHEMBL3314352

SMILES CN(C)Cc1ccc2CN(CCc2c1)C(=O)c1cc2cc(Br)ncc2n1C

InChI Key InChIKey=AURQGFNAFLUKPW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50045831   

LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human cardiac slowly activating delayed rectifier K+ channel expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Nav1.5 expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 3.12E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2D6 after 20 to 50 mins by high-throughput fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 280nMAssay Description:Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPyroglutamylated RF-amide peptide receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50045831(CHEMBL3314352)
Affinity DataIC50: 240nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed