BDBM50045488 CHEMBL3310123

SMILES [#6]C1([#8])c2ccccc2-c2ccc(cc12)-[#6](=O)\[#7]=[#6](\[#7])-[#7]

InChI Key InChIKey=HFGIWMGRIZXUGS-UHFFFAOYSA-N

Data  8 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50045488   

Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataIC50: 52nMAssay Description:Inhibition of human 5-HT2B receptor expressed in HEK293-EBNA cells assessed as [3H]PI metabolism by by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataIC50: 59nMAssay Description:Inhibition of human 5-HT7 receptor expressed in CHO cells assessed as cAMP production by EIA systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2B receptor expressed in HEK293-EBNA cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]HT from human 5-HT7 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi:  390nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50045488(CHEMBL3310123)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed