BDBM50045380 (20RS)-8-ethyl-8-hydroxy-8,9,12,14-tetrahydro-11H-[1,3]dioxolo[5,4-f]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-9,12-dione::CHEMBL328461

SMILES CCC1(O)C(=O)OCc2c1cc1-c3nc4ccc5OCOc5c4cc3Cn1c2=O

InChI Key InChIKey=OIWIDLBKGFKTHJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50045380   

TargetDNA topoisomerase 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50045380((20RS)-8-ethyl-8-hydroxy-8,9,12,14-tetrahydro-11H-...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Topoisomerase I by cleavage complex formation in intact human HL-60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed