BDBM50045292 (S)-2-[(S)-2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-pent-4-enoic acid ((1S,2R,3S)-1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl)-amide::2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-pent-4-enoic acid (1-cyclohexylmethyl-2,3-dihydroxy-5-methyl-hexyl)-amide::CHEMBL62380

SMILES CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC=C)NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1

InChI Key InChIKey=YTIOGZLHYJDYTK-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50045292   

TargetRenin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045292(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against monkey reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045292(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataIC50: 0.200nMAssay Description:The compound was evaluated for inhibitory activity against monkey plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetRenin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045292(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataIC50: 0.160nMAssay Description:In vitro inhibitory activity against monkey plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetCathepsin D(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045292(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity against human cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastricsin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045292(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataKi:  8nMAssay Description:Binding affinity against human gastricsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPepsin A-5(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045292(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataKi:  13nMAssay Description:Binding affinity against human pepsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin E(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50045292(2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propion...)
Affinity DataKi:  17nMAssay Description:Binding affinity against human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed