BDBM50044974 CHEMBL3309762

SMILES Oc1ccc(\C=C2/SC(=S)N(CC(=O)Nc3ccc(Oc4ccc(Cl)cc4)cc3)C2=O)c(O)c1

InChI Key InChIKey=KVSFSWTXQXDIMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044974   

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044974(CHEMBL3309762)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044974(CHEMBL3309762)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed