BDBM50043707 CHEMBL3356004

SMILES Cc1cc(NS(=O)(=O)c2ccccc2)c2ccccc2c1Oc1ncccc1-c1ccnc(N[C@H]2CC[C@H](N)CC2)n1

InChI Key InChIKey=RCOILDNJZSSEPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043707   

LigandPNGBDBM50043707(CHEMBL3356004)
Affinity DataIC50: 45nMAssay Description:Inhibition of human IRE1alpha using 5'[6FAM]-GAGUCCGCAGCACUC-[BHQ1]3' substrate by biochemical fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50043707(CHEMBL3356004)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human wild type JNK3 using biotinylated ATF2 substrate assessed as phosphorylation at thr53 on ATF2 by fluorescent plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed