BDBM50043471 (2,5-Difluoro-phenyl)-{[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenyl]-methyl-amino}-acetic acid::CHEMBL134754

SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)N(C)C(C(O)=O)c1cc(F)ccc1F

InChI Key InChIKey=YRGPNLQAYCXLSM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043471   

TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043471((2,5-Difluoro-phenyl)-{[4-(2-ethyl-5,7-dimethyl-im...)
Affinity DataIC50: 100nMAssay Description:In vitro antagonist activity against angiotensin II receptor type 1 in rabbit aorta using [125I]-Sar, Ile AII.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043471((2,5-Difluoro-phenyl)-{[4-(2-ethyl-5,7-dimethyl-im...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed