BDBM50043341 CHEMBL3355059

SMILES COc1cc(ccc1C(=O)Nc1ccc2CCNCCc2c1)-c1cn[nH]c1

InChI Key InChIKey=GMZCYCKIXQZORP-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50043341   

TargetMaternal embryonic leucine zipper kinase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043341(CHEMBL3355059)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of MELK kinase (unknown origin) using KKLNRTLSFAEPG/gamma[33P]ATP by Millipore kinase/scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043341(CHEMBL3355059)
Affinity DataIC50: 37nMAssay Description:Inhibition of MELK kinase (unknown origin) using biotinylated ZIP-tide peptide/gamma[33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043341(CHEMBL3355059)
Affinity DataIC50: 37nMAssay Description:Inhibition of MELK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetMyosin light chain kinase, smooth muscle(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043341(CHEMBL3355059)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of MLCK (unknown origin) by Millipore kinase analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
LigandPNGBDBM50043341(CHEMBL3355059)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of CAMK2gamma (unknown origin) by Millipore kinase analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043341(CHEMBL3355059)
Affinity DataIC50: 7.60E+5nMAssay Description:Inhibition of Mnk2 (unknown origin) by Millipore kinase analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
LigandPNGBDBM50043341(CHEMBL3355059)
Affinity DataIC50: 8.10E+5nMAssay Description:Inhibition of CAMK2delta (unknown origin) by Millipore kinase analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043341(CHEMBL3355059)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Flt3 (unknown origin) by Millipore kinase analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50043341(CHEMBL3355059)
Affinity DataIC50: 200nMAssay Description:Inhibition of MELK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed