BDBM50042963 (E)-3-(3,4-Dihydroxy-phenyl)-1-phenyl-propenone::3,4-dihydroxychalcone::3-(3,4-Dihydroxy-phenyl)-1-phenyl-propenone::3-(3,4-dihydroxyphenyl)-1-phenylprop-2-en-1-one::CHEMBL129510

SMILES Oc1ccc(\C=C\C(=O)c2ccccc2)cc1O

InChI Key InChIKey=HHKVOYUYPYZFHJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50042963   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042963(3,4-dihydroxychalcone | (E)-3-(3,4-Dihydroxy-pheny...)
Affinity DataIC50: 43nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Northern Kentucky University

Curated by ChEMBL
LigandPNGBDBM50042963(3,4-dihydroxychalcone | (E)-3-(3,4-Dihydroxy-pheny...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of bovine xanthine oxidase assessed as conversion of xanthine to uric acid by spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50042963(3,4-dihydroxychalcone | (E)-3-(3,4-Dihydroxy-pheny...)
Affinity DataIC50: 2.30E+3nMAssay Description:Compound concentration required to reduce HIV-1 Integrase 3'-processing activity by 50%More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042963(3,4-dihydroxychalcone | (E)-3-(3,4-Dihydroxy-pheny...)
Affinity DataIC50: 43nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50042963(3,4-dihydroxychalcone | (E)-3-(3,4-Dihydroxy-pheny...)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase (HIV-1-IN)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed